KMUS crosslinker
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| PCL033_0050 | 50 mg | Enquire | in stock | |
| PCL033_0100 | 100 mg | Enquire | in stock |
- IUPAC Name: 11-(maleimido)undecanoic acid N-succinimidyl ester
- Synonyms: 11-(maleimido)undecanoic acid N-succinimidyl ester, 11-(maleimidyl)undecanoic acid succinimidyl ester, 11-maleimidylundecanoic acid N-succinimidyl ester, N-maleimidylundecanoic acid succinimidyl ester, maleimidylundecaneic acid N-succinimidyl ester, maleimidylundecanoic acid N-succinimidyl estermaleimidoundecanoic acid N-succinimidyl ester, N-succinimidyl-11-(maleimidyl)undecanoate, N-(11-maleimidoundecanoyloxy)succinimide, N-succinimidyl 11-(maleimido)undecanoate
- CAS: 87981-04-2
- Smiles: O=C(CC1)N(OC(CCCCCCCCCCN2C(C=CC2=O)=O)=O)C1=O
- Chemical formula: C19H26N2O6
- Molecular weight: 378.425
- Purity: 95%+
KMUS is a amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a long spacer arm (16.3 angstroms).
Features of KMUS:
• Reactive groups: sulfo-NHS ester and maleimide
• Reactive toward: amino and sulfhydryl groups
• Long aliphatic spacer arm compared to GMBS
• NHS ester reacts with primary amines at pH 7-9, forming a stable amide bond
• Maleimide reacts with -SH groups at pH 6.5-7.5, forming a stable thioether bond
• Non-cleavable