DTSSP crosslinker
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| PCL037_0050 | 50 mg | Enquire | in stock | |
| PCL037_0100 | 100 mg | Enquire | in stock |
- IUPAC Name: 3,3'-dithiobis(sodiumsulfosuccinimidyl) propionate
- Synonyms: DTSSP, 3,3'-dithiobis(sulfosuccinimidyl propionate),
- CAS: 81069-02-5 (of acid)
- Smiles: O=C(ON1C(CC(S([O-])(=O)=O)C1=O)=O)CCSSCCC(ON2C(CC(S(=O)([O-])=O)C2=O)=O)=O.[Na+].[Na+]
- Chemical formula: C14H14N2O14S4Na2
- Molecular weight: 608.51
- Purity: 95%+
3,3´-Dithiobis(sulfosuccinimidylpropionate) (DTSSP) is a homobifunctional crosslinker that is cell membrane impermeable. DTSSP has primary amine-reactive N-hydroxysulfosuccinimide (Sulfo-NHS) esters at both ends of a cleavable, 8-atom (12.0 angstrom) spacer arm. DTSSP contains a reducible disulfide (thiol) bond in the spacer arm that make it a good choice for various applications.
DTSSP is ideal for aqueous crosslinking reactions. DTSSP can be used to crosslink extracellular and membrane proteins. If intracellular crosslinking is desired, then DSP, the water insoluble analog of DTSSP can be used for your research