BMPS crosslinker
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| PCL030_0050 | 50 mg | Enquire | in stock | |
| PCL030_0100 | 100 mg | Enquire | in stock |
- IUPAC Name: 3-maleimidopropionic acid N-hydroxysuccinimide ester
- Synonyms: 3-maleimidopropionic acid N-hydroxysuccinimide ester, N-succinimidyl 3-maleimidopropionate, 2,5-dioxopyrrolidin-1-yl 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoate, BMPS
- CAS: 55750-62-4
- Smiles: O=C(CC1)N(OC(CCN2C(C=CC2=O)=O)=O)C1=O
- Chemical formula: C11H10N2O6
- Molecular weight: 266.21
- Purity: 95%+
BMPS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short spacer arm (5.9 Å).
Features of BMPS:
• Reactive groups: NHS ester and maleimide
• Reactive towards: amino and sulfhydryl groups
• C3-homolog of aliphatic spacer series which includes AMAS, BMPS, GMBS and EMCS
• NHS ester end couples with primary amines at pH 7-9, forming stable amide bonds
• Maleimide reacts with -SH groups at pH 6.5-7.5, forming stable thioether linkages
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO)
• Short aliphatic spacer has low potential for eliciting an immune response