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bis-Maleimidoethane (BMOE)

Cat. # Quantity Price Lead time Buy this product
PCL029_0050 50 mg Enquire in stock
PCL029_0100 100 mg Enquire in stock
  • IUPAC Name: 1,1'-(ethane-1,2-diyl)bis(1H-pyrrole-2,5-dione)
  • Synonyms: 1,2-bis(maleimido)ethanebis-maleimidoethane1,1’-(ethane-1,2-diyl)bis(1H-pyrrole-2,5-dione), BMOE
  • CAS: 5132-30-9
  • Smiles: O=C(C=C1)N(CCN2C(C=CC2=O)=O)C1=O
  • Chemical formula: C10H8N2O4
  • Molecular weight: 220.18
  • Purity: 95%+

BMOE is a short-arm, maleimide crosslinker for covalent, irreversible conjugation between sulfhydryl groups (e.g., protein or peptide cysteines).

Features of BMOE:

• Reactive groups: maleimide (both ends)
• Reactive towards: sulfhydryl groups
• Short (8.0Å), sulfhydryl-to-sulfhydryl crosslinker, composed of maleimide groups and 7-atom spacer arm
• Shortest bismaleimide crosslinker available for close proximity crosslinking
• Water-insoluble—dissolve first in DMF or DMSO, then add to aqueous reaction buffers
• Noncleavable