Alcohol CF3-reagent (Togni Reagent I)
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| HYP002_1 | 1 g | 52,00 € | in stock | |
| HYP002_5 | 5 g | 170,00 € | in stock | |
| HYP002_10 | 10 g | 270,00 € | in stock | |
| HYP002_50 | 50 g | 1.220,00 € | in stock | |
| HYP002_100 | 100 g | 2.315,00 € | in stock | |
| HYP002_1000 | 1000 g | Enquire | in stock |
- IUPAC Name: 3,3-Dimethyl-1-(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole
- Synonyms: Togni reagent I, Alcohol-CF3 Togni reagent
- CAS: 887144-97-0
- Smiles: CC(OI1C(F)(F)F)(C)C2=C1C=CC=C2
- Chemical formula: C10H10F3IO
- Molecular weight: 330.09
- Purity: 98%+
Alcohol CF3-reagent, more commonly termed Togni reagent I, is the first hypervalent iodine-CF3 reagent that was commercialized. From the both Togni reagents, this reagent is clearly much better soluble in organic solvents (even in pentane). The reagent contains a relatively basic alkoxide group, meaning that formal oxidative insertion on a metal centre creates a new higher valent CF3-metal complex containing 2-(2-iodophenyl)-propanolate as a ligand. Such inherent basicity can be helpful for design of catalytic trifluoromethylation processes in which deprotonation generates the active nucleophile.